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Totally, we identified 4196 phosphosites in human urine proteins by mass spectrometry in replicated tests, a number which is dozens of times larger than those previously reported.
Therefore, this strategy may have great potential in urine-based phosphoprotein biomarker screening and drug response studies.
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The majority of the most influential sacred texts in history were written in the ancient world.
The ideas and beliefs of the ancients tell us who they were at their very sense of being, what they believed and how they understood the world surrounding them.
Effective fractionation is critical for sample handling before mass-spectrometry-based proteomics.
Proteome analysis routinely involves digesting intact proteins followed by inferred protein identification using mass spectrometry.